Pettersson (lower body) was designated for injured reserve Tuesday.
Pettersson (lower body) was labeled week-to-week by head coach Mike Sullivan on Monday, Wes Crosby of NHL.com reports.
Pettersson logged an assist in Saturday's 4-3 loss to the Canucks.
Pettersson recorded new personal bests in goals (four), assists (26) and games played (82) this season.
Pettersson scored his fourth goal of the season in Tuesday's 5-2 loss to the Devils.
Pettersson scored a goal on three shots and registered an assist in Thursday's 4-3 overtime loss to Vancouver.
Pettersson notched four assists with one blocked shot and a plus-5 rating in Wednesday's 7-0 win over the Islanders.
Pettersson recorded an assist against the Lightning on Thursday.
Pettersson posted an assist, two PIM and a plus-5 rating in Saturday's 10-2 win over the Sharks.
Pettersson (lower body) will be in the lineup against the Blue Jackets on Thursday, Penguins radio play-by-play announcer Josh Getzoff reports.