Yakupov is set to sign a two-year contract with SKA St. Petersburg of the KHL, Igor Eronko of Sport-Express reports.
Yakupov wasn't tendered a qualifying offer Monday and will now become an unrestricted free agent, Mike Chambers of the Denver Post reports.
Yakupov watched all six games of the Avs' first-round series against the Predators.
Yakupov was a healthy scratch for the fourth consecutive game during Friday's 7-1 win over Minnesota.
Yakupov recorded one shot through 9:10 of ice time (2:09 with the man advantage) during Thursday's 5-3 win over San Jose.
Yakupov (illness) will rejoin the action for Saturday's home game against the Lightning, Adrian Dater of BSN Denver reports.
Yakupov (illness) will not be active for Thursday night's home game against the Panthers.
Yakupov (illness) won't play Tuesday against the Capitals, Tom Gulitti of NHL.com reports.
Yakupov (illness) could draw into the lineup for Tuesday's game against the Capitals if Alex Kerfoot (lower body) is unavailable.
Yakupov will miss Monday's road tilt against the Penguins due to an illness, Mike Chambers of The Denver Post reports.