Siegenthaler underwent a lower-body procedure during the break for the 4 Nations Face-Off and will be re-evaluated in 2-3 weeks, the Devils announced Tuesday.
Siegenthaler (undisclosed) was placed on injured reserve Tuesday.
Per Amanda Stein of the Devils' official site, Siegenthaler (undisclosed) will see a specialist to determine the length of time he will be out of the lineup, coach Sheldon Keefe said Thursday.
Siegenthaler scored a goal in Tuesday's 3-2 loss to the Ducks.
Siegenthaler notched an assist and three blocked shots in Friday's 4-2 win over the Hurricanes.
Siegenthaler was held off the scoresheet for the 12th straight game in Tuesday's 2-1 overtime loss to the Maple Leafs.
Siegenthaler (concussion) will play Tuesday versus the Penguins, Amanda Stein of the Devils' official site reports.
Siegenthaler is expected to miss time with a concussion. Head coach Travis Green told reporters Wednesday, "He'll be out for an extended period of time," per Amanda Stein of the Devils' official site.
Siegenthaler (upper body) was injured in Monday's 3-1 loss to the Rangers late in the second period, Dan Rosen of NHL.com reports.
Siegenthaler (foot) will be an option versus Washington on Tuesday. Coach Lindy Ruff told reporters, "Available to play, we'll look at getting him back in tomorrow (vs. Washington)," Amanda Stein of the Devils' official site reports.