The Giants transferred Murphy (knee) to the 60-day injured list Wednesday, Andrew Baggarly of The Athletic reports.
Giants manager Bob Melvin said Monday that Murphy is expected to be sidelined 4-to-6 weeks after being diagnosed with a left knee sprain, Maria I. Guardado of MLB.com reports.
The Giants placed Murphy on the 10-day injured list with a left knee sprain Sunday, Shayna Rubin of the San Francisco Chronicle reports.
Murphy was removed from Saturday's game versus the Phillies in the second inning with an apparent knee injury, Shayna Rubin of the San Francisco Chronicle reports.
Murphy will start at catcher and bat sixth in Wednesday's game against the Nationals, Susan Slusser of the San Francisco Chronicle reports.
Murphy has gone 2-for-7 with a double and three strikeouts over his first three Cactus League games.
Murphy agreed to a two-year, $13 million contract with the Giants on Monday, Jon Heyman of the New York Post reports.
Murphy is slated to have imaging performed on his injured thumb Friday in order to determine whether he's ready to return to baseball activities, the team's official site reports.
Murphy has been diagnosed with a small fracture in his left thumb and has been shut down for the last 10 days. He'll be re-evaluated Sept. 22, Shannon Drayer of Seattle Sports 710 AM reports.
Murphy (thumb) is visiting with a specialist and is expected to be cleared to increase baseball activities this week, Ryan Divish of The Seattle Times reports.