The Blue Jays outrighted Espino to Triple-A Buffalo on Wednesday, Arden Zwelling of Sportsnet.ca reports.
The Blue Jays designated Espino for assignment Sunday.
The Blue Jays optioned Espino to Triple-A Buffalo on Thursday.
Espino (0-1) took the loss Wednesday against the Orioles, allowing four runs on five hits and three walks over four innings. He struck out one.
The Blue Jays recalled Espino from Triple-A Buffalo ahead of his scheduled start Wednesday in Baltimore.
Espino (undisclosed) has given up seven earned runs on 10 hits and one walk while striking out three over 5.2 innings in his two starts since being reinstated from Triple-A Buffalo's 7-day injured list July 4.
Triple-A Buffalo placed Espino on its 7-day injured list Wednesday with an unspecified injury.
Espino was optioned to Triple-A Buffalo on Saturday.
The Blue Jays selected Espino's contract from Triple-A Buffalo on Friday, Hazel Mae of Sportsnet reports.
Espino allowed three runs on six hits over four innings in Saturday's Grapefruit League game against the Yankees. He struck out four without walking a batter.