Matthews didn't factor in the decision in Game 2 of Sunday's doubleheader against the Red Sox. He allowed a run on two hits with six strikeouts and two walks over 4.2 innings.
Matthews (1-3) took the loss Friday, giving up four runs on nine hits and a walk over five innings as the Twins were downed 5-0 by the Royals. He struck out four.
Matthews is scheduled to start Monday's game against the Padres at Petco Park.
Matthews (1-0) picked up the win in Tuesday's 13-3 rout of the Royals, giving up two runs on five hits over five innings. He struck out five without walking a batter.
The Twins selected Matthews' contract from Triple-A St. Paul on Tuesday. He'll start Tuesday's game against the Royals.
The Twins are expected to call up Matthews from Triple-A St. Paul, Jeff Passan of ESPN.com reports.
Twins president of baseball operations Derek Falvey said Friday that Matthews is "certainly a name we're talking about" when considering options for the major-league rotation, Bobby Nightengale of the Minneapolis Star Tribune reports.
The Twins have promoted Matthews from Double-A Wichita to Triple-A St. Paul, Do-Hyoung Park of MLB.com reports.
The Twins promoted Matthews from High-A Cedar Rapids to Double-A Wichita on Monday.