The White Sox optioned Nastrini to Triple-A Charlotte on Monday.
Nastrini (0-2) allowed six runs (five earned) on six hits and five walks over three innings to take the loss Sunday against the Phillies. He struck out three.
Nastrini is scheduled to start Sunday's game in Philadelphia.
The White Sox selected Nastrini's contract from Triple-A Charlotte on Monday.
Nastrini is expected to be called up from Triple-A Charlotte and start Chicago's series opener with the Royals on Monday, Scott Merkin of MLB.com reports.
White Sox general manager Chris Getz revealed Thursday that Nastrini has been battling an illness lately at Triple-A Charlotte, Scott Merkin of MLB.com reports.
Nastrini, who is scheduled to make his first start of the season for Triple-A Charlotte on Wednesday, could be called up to start for the White Sox next Monday in Cleveland, Daryl Van Schouwen of the Chicago Sun-Times reports.
Nastrini has allowed just one run over seven innings this spring as he attempts to win a spot in the White Sox' rotation, Daryl Van Schouwen of the Chicago Sun-Times reports.
The Dodgers traded Nastrini, Jordan Leasure and Trayce Thompson to the White Sox on Friday in exchange for Lance Lynn and Joe Kelly, Jeff Passan of ESPN.com reports.
Nastrini (undisclosed) made his season debut Thursday after being assigned to Double-A Tulsa, pitching three scoreless innings and striking out four in a 3-0 win over Wichita. He scattered one hit and three walks in the 47-pitch outing.