Triple-A Toledo placed Lange (lat) on its full-season injured list Friday.
Lange (upper body) suffered a right lat avulsion and is scheduled to undergo surgery next week, Evan Petzold of the Detroit Free Press reports.
The Tigers optioned Lange to Triple-A Toledo on Thursday.
Lange earned the save in Wednesday's 4-1 win over the Cardinals, recording two strikeouts and a walk over 1.1 scoreless innings.
Lange (0-1) allowed five unearned runs to take the loss in the first game of Saturday's doubleheader against the Twins. He walked two and retired two batters via strikeout.
Lange earned the save in Friday's 5-4 win over the A's, striking out the lone batter he faced in a third of an inning.
Lange did not appear in Thursday's 1-0 win over the White Sox. Jason Foley recorded the final two outs to earn his first save of the season.
Lange allowed one hit in a scoreless ninth inning to secure the save in Sunday's 5-2 win over the Guardians. He struck out two.
Lange struck out one in a perfect inning to earn the save in Sunday's 5-3 win over the Angels.
Lange worked around a hit and a walk to record a scoreless inning and earn the save in Sunday's 3-2 win over the White Sox.