The Pirates reinstated Holderman (wrist) from the 15-day injured list Sunday.
Holderman (wrist) will start a rehab assignment with Triple-A Indianapolis on Tuesday, Danny Demilio of PittsburghBaseballNow.com reports.
Holderman (wrist) threw a live batting practice session Friday consisting of 22 to 25 pitches, Andrew Destin of the Pittsburgh Post-Gazette reports.
Holderman (wrist) threw a bullpen session Wednesday, Alex Stumpf of MLB.com reports.
The Pirates placed Holderman on the 15-day injured list Thursday with a right wrist sprain, Noah Hiles of the Pittsburgh Post-Gazette reports.
Holderman (1-3) allowed two earned runs on three hits and a walk while striking out one across one inning to take the loss Sunday against the Rays.
Holderman (2-0) allowed two hits but threw a scoreless eighth inning to earn the win Tuesday against the Cardinals.
The Pirates reinstated Holderman (illness) from the 15-day injured list Thursday.
Holderman (illness) could be activated from the injured list Thursday, Andrew Destin of the Pittsburgh Post-Gazette reports.
Pirates director of sports medicine Todd Tomczyk said Monday that Holderman (illness) will throw a live batting practice session within the next few days, Jason Mackey of the Pittsburgh Post-Gazette reports.