Arias went 1-for-4 with a stolen base in Friday's 6-2 loss to Atlanta.
Arias is out of the lineup for Wednesday's game against the Red Sox.
Arias will start in center field and bat seventh in Wednesday's game against the Red Sox.
Arias went 2-for-3 with a solo home run, a walk and two total runs scored in Sunday's 8-7 extra-inning win over the Yankees.
Arias went 2-for-5 with two RBI, two runs and a stolen base during Saturday's 12-3 win against the A's.
Guardians manager Stephen Vogt announced Friday that Brayan Rocchio will begin the season as the club's primary shortstop, priming Arias to fill a utility role, Tom Withers of the Associated Pressreports.
Arias (illness) is starting at shortstop and batting fifth in Friday's Cactus League game against the Royals.
Arias was scratched from Sunday's Cactus League lineup versus the Reds due to an illness, Mandy Bell of MLB.comreports.
Arias (wrist) will bat in the cleanup spot for Sunday's spring training game against the Mariners.
Cleveland placed Arias on the 10-day injured list Wednesday with a fractured right wrist.