The Marlins outrighted Pache to Triple-A Jacksonville on Wednesday.
The Marlins designated Pache for assignment Tuesday, Christina De Nicola of MLB.com reports.
Pache is out of the lineup for Monday's game against the Pirates.
Pache went 1-for-4 with a run scored, an RBI and a stolen base in Sunday's win over Atlanta.
The Marlins claimed Pache off waivers from the Orioles on Friday, Christina De Nicola of MLB.com reports.
The Orioles designated Pache for assignment Thursday.
The Orioles acquired Pache and reliever Seranthony Dominguez from the Phillies in exchange for outfielder Austin Hays on Friday.
Pache will start in center field and bat ninth in Sunday's game against the Pirates.
Pache will start in center field and bat eighth in Tuesday's game versus the Padres.
Pache will start in left field and bat seventh in Wednesday's game against the Reds.