Castillo (hand) has given up three earned runs on five hits and no walks while striking out two batters over 2.2 innings in three appearances since being reinstated from Triple-A Reno's 7-day injured list July 19.

Castillo is day-to-day after tests on his left hand came back negative, Theo Mackie of The Arizona Republic reports.

Castillo agreed to a minor-league contract with the Diamondbacks on Monday.

Castillo was outrighted Thursday to Triple-A Jacksonville, Jordan McPherson of the Miami Herald reports.

Miami acquired Castillo from the Padres on Tuesday for cash considerations and optioned him to Triple-A Jacksonville.

Castillo was designated for assignment Thursday.

Castillo was optioned to Triple-A El Paso on Friday, Jeff Sanders of The San Diego Union-Tribune reports.

San Diego recalled Castillo from Triple-A El Paso on Tuesday.

Castillo was activated from the 15-day injured list and optioned to Triple-A El Paso by the Padres on Monday.

Castillo (shoulder) is set to begin a rehab assignment Tuesday with Triple-A El Paso, Jeff Sanders of The San Diego Union-Tribune reports.