The Orioles released Mejias-Brean on Tuesday, Roch Kubatko of MASNSports.com reports.
Mejias-Brean signed a minor-league contract with the Orioles on Wednesday, Dan Connolly of The Athletic reports.
The Padres released Mejias-Brean on Saturday.
The Padres added Mejias-Brean to their 60-man roster pool Sunday, AJ Cassavell of MLB.com reports.
Mejias-Brean was outrighted to Triple-A El Paso on Monday.
Mejias-Brean went 3-for-4 with a home run, a double, three RBI and a walk in Sunday's 6-4 win over Arizona.
Mejias-Brean got the start at shortstop Wednesday, going 1-for-3 with a two-run home run.
Mejias-Brean is starting at first base and batting sixth in Wednesday's game against the Cubs.
Mejias-Brean had his contract selected from Triple-A El Paso on Tuesday.
Mejias-Brean was traded to the Mariners for a player to be named later, Zach Buchanan of the Cincinnati Enquirer reports.