Mathurin is slated to undergo season-ending surgery to repair a torn labrum in his right shoulder, Adrian Wojnarowski of ESPN reports.
Pacers coach Rick Carlisle said Thursday that Mathurin (shoulder) will miss the Pacers' next three games, Tony East of SI.com reports.
Mathurin has been ruled out for Thursday's game against the Timberwolves due to a right shoulder sprain.
Mathurin is questionable for Tuesday's game against Dallas due to left foot soreness.
Mathurin recorded 14 points (5-14 FG, 3-7 3Pt, 1-1 FT), 11 rebounds, five assists and three steals across 33 minutes during Sunday's 133-111 victory over the Mavericks.
Mathurin registered 15 points (5-14 FG, 1-3 3Pt, 4-5 FT), six rebounds, five assists and one steal over 35 minutes during Thursday's 129-115 victory over the Pistons.
Mathurin is in the starting lineup to face the Pistons on Thursday.
Mathurin (knee/illness) claimed Rising Stars MVP honors Friday after scoring four points (1-3 FG, 0-1 3Pt, 2-2 FT) and adding two assists and one steal in 7:20 of court time in Team Jalen's 26-13 win over Team Detlef in the final.
Mathurin (knee) has been ruled out for Wednesday's game in Toronto, Dustin Dopirak of The Indianapolis Star reports.
Mathurin is listed as questionable for Wednesday's game in Toronto due to a bruised right knee.