Portland announced Wednesday that Ayton has been diagnosed with a left calf strain and that he will be re-evaluated in four weeks.

Ayton (calf) is out for Wednesday's game versus the Nuggets.

Ayton racked up six points (2-6 FG, 2-4 FT), 14 rebounds, two assists and one block in 32 minutes during Saturday's 114-98 loss to the Timberwolves.

Ayton logged 25 points (9-22 FG, 0-1 3Pt, 7-8 FT), 20 rebounds, two assists, one block and one steal over 42 minutes during Monday's 121-119 overtime win over the Suns.

Ayton notched 24 points (11-12 FG, 2-3 FT), seven rebounds, two assists and one block over 33 minutes during Saturday's 127-108 victory over the Suns.

Ayton provided 22 points (10-12 FG, 2-4 FT), eight rebounds, three assists and three steals over 35 minutes during Thursday's 119-90 victory over the Magic.

Ayton (knee) tallied 21 points (9-19 FG, 0-1 3Pt, 3-4 FT), 14 rebounds, two assists, one steal and one block across 34 minutes in Tuesday's 125-112 win over the Bucks.

Ayton (knee) has been ruled out for Friday's game against the Hornets.

Ayton (knee) won't play in Thursday's game versus the Magic, Casey Holdahl of the Trail Blazers' official site reports.

Ayton (knee) has been listed as questionable for Thursday's game against the Magic, Sean Highkin of Rip City Radio 620 Portland reports.