Highsmith is listed as available for Friday's game versus the Pacers despite dealing with a left knee bone bruise.
Highsmith had seven points (2-5 FG, 1-4 3Pt, 2-4 FT), two rebounds, one block and five steals over 33 minutes during Sunday's 95-94 victory over the Timberwolves.
Highsmith will start Sunday's game against the Timberwolves, Will Guillory of The Athletic reports.
Highsmith finished Friday's 135-122 loss to Denver with 15 points (6-10 FG, 3-6 3Pt) and two assists over 35 minutes.
Highsmith won't start Wednesday's regular-season opener against the Magic.
Highsmith is in the starting lineup for Friday's preseason game against the Grizzlies.
Highsmith and the Heat agreed to a two-year, $11 million deal Monday, ESPN's Adrian Wojnarowski reports.
Highsmith posted nine points (4-8 FG, 0-4 3Pt, 1-2 FT), six rebounds, three assists, three steals and one block across 28 minutes in Wednesday's 105-104 Play-In Game loss to the 76ers.
Highsmith produced 20 points (7-9 FG, 5-6 3Pt, 1-3 FT), six rebounds, one assist and one steal over 28 minutes off the bench during Friday's 142-82 win over the Trail Blazers.
Highsmith closed with 18 points (7-10 FG, 4-4 3Pt), five rebounds, two assists and one steal over 25 minutes during Sunday's 121-84 win over the Cavaliers.