The San Francisco 49ers acquired defensive lineman Charles Omenihu from the Houston Texans for a sixth-round draft pick in 2023.

The New Orleans Saints acquired running back Mark Ingram from the Houston Texans for a seventh-round draft pick in 2024.

The New Orleans Saints acquired cornerback Bradley Roby from the Houston Texans for a third-round draft pick in 2022 and a conditional sixth-round draft pick in 2023.

The New York Jets acquired defensive end/linebacker Shaq Lawson from the Houston Texans for a sixth-round draft pick in 2022.

The Seattle Seahawks acquired cornerback John Reid from the Houston Texans for a conditional seventh-round draft pick in 2023.

The Houston Texans acquired cornerback Ka'Dar Hollman from the Green Bay Packers for a seventh-round draft pick in 2022.

The New York Giants acquired cornerback Keion Crossen from the Houston Texans for a sixth-round draft pick in 2023.

The Green Bay Packers acquired wide receiver Randall Cobb from the Houston Texans for a sixth-round draft pick in 2022.

The Houston Texans acquired wide receiver Anthony Miller and a seventh-round draft pick in 2022 from the Chicago Bears for a fifth-round draft pick in 2022.

The Houston Texans acquired quarterback Ryan Finley and a seventh-round draft pick in 2021 from the Cincinnati Bengals for a sixth-round draft pick in 2021.

The Houston Texans acquired tight end Ryan Izzo from the New England Patriots for a seventh-round draft pick in 2022.

The Houston Texans acquired offensive lineman Marcus Cannon, a fifth-round draft pick in 2021 and a sixth-round draft pick in 2021 from the New England Patriots for a fourth-round draft pick in 2021 and a sixth-round draft pick in 2021.

The Houston Texans acquired linebacker/defensive end Shaq Lawson and a sixth-round draft pick in 2021 from the Miami Dolphins for linebacker Benardrick McKinney and a seventh-round draft pick in 2021.

The Dallas Cowboys acquired defensive lineman Eli Ankou from the Houston Texans for a seventh-round draft pick in 2022.

The Houston Texans acquired wide receiver Brandin Cooks and a fourth-round draft pick in 2022 from the Los Angeles Rams for a second-round draft pick in 2020 (No. 57 overall).

The Arizona Cardinals acquired wide receiver DeAndre Hopkins and a fourth-round draft pick in 2020 from the Houston Texans for running back David Johnson, a second-round draft pick in 2020 and a fourth-round draft pick in 2021.

The Houston Texans acquired cornerback Gareon Conley from the Oakland Raiders for a third-round draft pick in 2020.

The Houston Texans acquired offensive tackle Laremy Tunsil, wide receiver Kenny Stills, a fourth-round draft pick in 2020 and a sixth-round draft pick in 2021 from the Miami Dolphins for a first-round draft pick in 2020, a first-round draft pick in 2021, a second-round draft pick in 2021, offensive tackle Julie'n Davenport and cornerback/safety Johnson Bademosi.

The Houston Texans acquired cornerback Keion Crossen from the New England Patriots for a sixth-round draft pick in 2020.

The Houston Texans acquired running back Carlos Hyde from the Kansas City Chiefs for offensive guard/tackle Martinas Rankin.

The Seattle Seahawks acquired defensive end/linebacker Jadeveon Clowney from the Houston Texans for linebackers Barkevious Mingo and Jacob Martin and a third-round draft pick in 2020.

The Houston Texans acquired running back Duke Johnson from the Cleveland Browns for a conditional fourth-round draft pick in 2020.

The Houston Texans acquired wide receiver Demaryius Thomas and a seventh-round draft pick in 2019 from the Denver Broncos for a fourth-round draft pick in 2019 and a seventh-round draft pick in 2019.

The Seattle Seahawks acquired offensive tackle Duane Brown and a 5th-round draft pick in 2018 from the Houston Texans for a 3rd-round draft pick in 2018 and a 2nd-round draft pick in 2019.

The Cleveland Browns acquired quarterback Brock Osweiler, a second-round draft pick in 2018 and a sixth-round draft pick in 2017 from the Houston Texans for a fourth-round draft pick in 2017.

The New England Patriots acquired wide receiver Keshawn Martin and a sixth-round draft pick in 2016 from the Houston Texans for a fifth-round draft pick in 2016.

The Chicago Bears acquired tight end Khari Lee from the Houston Texans for a 6th-round draft pick in 2017.

The Houston Texans acquired offensive lineman Chris Clark from the Denver Broncos for a 7th-round draft pick in 2016.

The Houston Texans acquired a third-round draft pick in 2015 (No. 70 overall) from the New York Jets for wide receiver DeVier Posey, a third-round draft pick in 2015 (No. 82 overall), a fifth-round draft pick in 2015 (No. 152 overall) and a seventh-round draft pick in 2015 (No. 229 overall).

The New York Jets acquired quarterback Ryan Fitzpatrick from the Houston Texans for a conditional seventh-round draft pick in 2016.

The St. Louis Rams acquired quarterback Case Keenum from the Houston Texans for a seventh-round draft pick in 2016.