The Bills traded Shakir's teammate Stefon Diggs to the Texans on Wednesday, just a few weeks after Gabe Davis signed as a free agent with the Jaguars.
Shakir's teammate Gabe Davis has been ruled out of Sunday's playoff opener against the Steelers due to a knee injury.
Shakir caught all six of his targets for 105 yards in Sunday's 21-14 victory over the Dolphins.
Shakir caught all four of his targets for 39 yards and carried once for 10 yards in Sunday's 27-21 win over the Patriots.
Shakir failed to secure his lone target in Sunday's 31-10 win over the Cowboys.
Shakir caught one of his two targets for 24 yards in Monday's 24-22 loss to the Broncos.
Shakir caught all four targets for 35 yards in Buffalo's 29-25 loss to the Patriots on Sunday.
Shakir reeled in his lone target for 13 yards in Sunday's 14-9 win over the Giants.
Shakir (head) wasn't listed on Buffalo's injury report Wednesday, Chris Brown of Bills Radio Network reports.
Shakir is being evaluated for a head injury and is uncertain to return to Sunday's game against the Dolphins.