Las Vegas signed Spiller to its practice squad Wednesday.
The Chargers are slated to waive Spiller, Ian Rapoport of NFL Network reports.
Spiller is slated to compete with rookie sixth-round pick Kimani Vidal for the No. 3 running back job behind Gus Edwards (undisclosed) and J.K. Dobbins (Achilles) during training camp, Alexander Insdorf of BoltBeat.com reports.
Spiller (coach's decision) is inactive for Sunday's Week 18 game against the Chiefs.
Spiller lost a yard on his lone carry and caught both of his targets for 10 yards in the 16-9 loss to the Broncos on Sunday.
Spiller recorded six carries for 19 yards in Sunday's 24-7 defeat to the Broncos.
Spiller is active for Sunday's game against the Broncos.
Spiller (illness) has been ruled out ahead of Sunday's game against the Packers, Jeff Miller of the Los Angeles Times reports.
Spiller (illness) is listed as questionable ahead of Sunday's game against the Packers.
Spiller rushed three times for three yards while securing his lone target for five yards in Sunday's 30-13 win over the Bears.