The Jaguars are in line to release Hyde on Friday, Adam Schefter of ESPN and Ian Rapoport of NFL Network report.
Jacksonville will place Hyde (concussion) on injured reserve Tuesday, ending his season, Michael DiRocco of ESPN.com reports.
Hyde (concussion) has been ruled out for Sunday's game against the Texans, John Shipley of SI.com reports.
Hyde (concussion) didn't participate at Thursday's practice.
Hyde is not practicing Wednesday due to a concussion, Mark Long of the Associated Press reports.
Hyde had one carry for two yards and caught one of two targets for six yards during Sunday's 20-0 loss to the Titans.
Hyde ran for 24 yards and one touchdown on nine carries against the Rams on Sunday.
Hyde had six carries for 16 yards and failed to catch his lone target during Sunday's 21-14 loss to the Falcons.
Hyde failed to catch his lone target during Sunday's 30-10 loss to the 49ers.
Hyde (shoulder) was a full participant in Friday's practice and doesn't have a designation for Sunday's game against the 49ers.