The Chargers signed Dotson to their practice squad Tuesday.
The Chargers waived Dotson on Saturday, Aaron Wilson of KPRC 2 Houston reports.
Dotson is inactive for Monday night's game against the Cowboys.
Dotson played a single snap in Sunday's 28-24 win over the Vikings.
Dotson carried the ball four times for six yards in Sunday's 27-24 overtime loss to the Chargers. He also caught two passes for 13 yards.
Dotson made Los Angeles' 53-man roster Tuesday, Daniel Popper of The Athletic reports.
Dotson has agreed to terms with the Chargers as an undrafted free agent.