Bigsby rushed 11 times for 42 yards and didn't catch his only target in Sunday's 32-25 loss to the Jets.
Bigsby carried seven times for 28 yards and caught his lone target for seven yards during Sunday's 23-20 loss to the Texas.
Bigsby (ankle) was a full participant in Wednesday's practice.
Bigsby (ankle) has been ruled out for Sunday's game at Detroit.
Coach Doug Pederson said Bigsby (ankle) will practice Friday, and he's optimistic the running back will be able to play Sunday against the Lions, Demetrius Harvey of The Florida Times-Union reports.
Bigsby (ankle) didn't practice Thursday.
Bigsby (ankle) didn't practice Wednesday.
Bigsby exited Sunday's game against the Vikings due to an ankle injury, John Oehser of the Jaguars' official site reports.
Bigsby (ankle) doesn't have a designation for Sunday's contest against the Vikings.
Bigsby (ankle) remained limited in practice Thursday.