Zylstra (knee) re-signed with the Lions on Monday.
Zylstra (knee) cleared waivers Wednesday and has reverted to Detroit's injured reserved.
The Lions waived Zylstra (knee) on Tuesday with an injury designation.
Zylstra injured his knee Monday, Ian Rapoport of NFL Network reports.
The Lions re-signed Zylstra, who was an exclusive rights free agent, on Monday, Aaron Wilson of KPRC 2 Houston reports.
Zylstra played 22 of the Lions' 60 snaps on offense and failed to haul in his lone target in Sunday's 20-16 win over the Packers.
Zylstra brought in five of six targets for 26 yards with three touchdowns during Saturday's 37-23 loss to Carolina.
Zylstra played 23 of the Lions' 68 snaps on offense and finished with two receptions for 18 yards on two targets in Sunday's 34-23 win over the Vikings.
Detroit signed Zylstra from its practice squad to the active roster Saturday ahead of Sunday's game at Chicago.
Detroit reverted Zylstra to the practice squad Monday, per the NFL's transaction log.