The Lions placed McNeill (knee) on injured reserve Tuesday.
McNeil sustained a ruptured ACL during Sunday's game versus the Bills, Ian Rapoport of NFL Network reports.
McNeill has been ruled out for the remainder of Sunday's game against Buffalo due to a knee issue.
McNeill (concussion) has no injury designation ahead of Sunday's matchup against the Bills.
The Lions signed McNeill to a four-year contract extension Tuesday, Ian Rapoport of NFL Network reports.
McNeill recorded four total tackles (two solo), including 2.0 sacks, in Sunday's 47-9 win over the Cowboys.
McNeill (shoulder) was a full participant at the Lions' practice Friday, Eric Woodyard of ESPN.com reports.
McNeil is considered day-to-day after leaving Sunday's win over the Cardinals with a shoulder injury, per Jordan Shultz of Bleacher Report.
McNeil (shoulder) has been ruled out for the rest of Sunday's game against the Cardinals.
McNeill exited Sunday's game against the Cardinals with a shoulder injury and is questionable to return.