Rousseau recorded seven total tackles (four solo), including 1.0 sacks and an additional two tackles for loss, in Sunday's 30-27 win over the Dolphins.
Rousseau recorded four tackles (three solo) and two passes defensed during Sunday's 31-10 win at Seattle.
The Bills will exercise Rousseau's 2025 fifth-year team option, Sal Capaccio of WGR Sports Radio 550 Buffalo reports.
Rousseau completed the 2023 regular season with 42 tackles, 5.0 sacks, four passes defensed, one forced fumble and one fumble recovery.
Rousseau had two tackles, one pass defensed and half a sack during Buffalo's 20-17 win over the Chiefs on Sunday.
Rousseau (foot) does not carry an injury designation ahead of Sunday's game versus the Giants.
Coach Sean McDermott said Friday that Rousseau (foot) is ruled out for Sunday's game against the Jaguars, Katherine Fitzgerald of The Buffalo News reports.
Rousseau (foot) did not participate at practice Wednesday, Chris Brown of the Bills' official site reports.
Rousseau finished the 2022 regular season with 37 tackles, eight sacks, four passes defended and one forced fumble over 13 games.
Rousseau (ankle) was a full participant in practice Monday.