Hufanga recorded eight tackles (two solo) during Thursday's 12-6 loss versus the Rams.
Hufanga (wrist) will play Sunday versus the Bears.
Hufanga (wrist) is listed as questionable ahead of Sunday's matchup against the Bears, Jennifer Lee Chan of NBC Sports Bay Area reports.
Hufanga (wrist) was designated to return from injured reserve Wednesday.
Coach Kyle Shanahan said Monday that Hufanga (wrist) will be designated for return from injured reserve this week, Nick Wagoner of ESPN.com reports.
Hufanga (wrist) was placed on injured reserve Wednesday
Head coach Kyle Shanahan said Tuesday that Hufanga has ligament damage in his wrist and will miss about a month, Matt Barrows of The Athletic reports.
Hufanga (wrist) has been ruled out for the rest of Sunday's game against the Cardinals, Eric Branch of the San Francisco Chronicle reports.
Hufanga (wrist) is considered questionable to return to Sunday's contest against the Cardinals, Nick Wagoner of ESPN.com reports.
Hufanga (ankle) was listed as a limited participant on the 49ers' injury report Thursday.