The Jaguars activated Hamilton (back) from the reserve/injured list Saturday.
The Jaguars designated Hamilton (back) for a return from injured reserve Thursday, Mia O'Brien of 1010 XL 92.5 FM Jacksonville reports.
Hamilton (back) will not be taking the trip to London and will miss each of the team's next two games, Michael DiRocco of ESPN.com reports.
Hamilton (back) will start the season on Jacksonville's injured reserve.
Hamilton (back) could return next week, according to head coach Doug Pederson, J.P. Shadrick of the Jaguars' official site reports.
Coach Doug Pederson said on Monday that Hamilton (back) remains "on the road to recovery," Mark Long on USA Today reports.
Hamilton (back) is dealing with a non-football related injury, Demetrius Harvey of the Florida Times-Union reports.
Hamilton (back) practiced Wednesday, John Shipley of SI.com reports.
The Jaguars signed Hamilton to a three-year, $34.5 million extension Wednesday, NFL Network's Ian Rapoport reports.
Hamilton (foot) is officially active for Sunday's game against the Giants.