Tranquill compiled 79 tackles (54 solo), 4.5 sacks and forced two fumbles during the 2023 regular season.
Tranquill (concussion) was a full participant in Wednesday's practice.
Tranquill (concussion) has been ruled out ahead of Sunday's game against the Bills, Matt McMullen of the Chiefs' official site reports.
Tranquill remains in concussion protocols Wednesday and will not practice.
Tranquill notched 11 tackles (seven solo), one sack and one forced fumble during Sunday's 24-9 loss to Denver.
Tranquill (neck) returned to practice Sunday, Pete Sweeney of ArrowheadPride.com reports.
Head coach Andy Reid told reporters Friday that Tranquill left practice early with a strained neck, Pete Sweeney of ArrowheadPride.com reports.
Tranquill is slated to sign a one-year, $5 million deal with the Chiefs on Friday, Jordan Schultz of TheScore.com reports.
Tranquill recorded 144 tackles (93 solo), five sacks, 10 tackles for loss as well forcing a fumble and recording an interception during the 2022-23 season.
Tranquill tallied nine tackles, including two for loss, in Sunday's 31-10 Week 17 win over the Rams.