The Bills placed Smoot (wrist) on injured reserve Tuesday.

Head coach Sean McDermott told reporters Monday that Smoot is set to undergo wrist surgery and will be placed on injured reserve, Alaina Getzenberg of ESPN.com reports.

Smoot left Sunday's 30-27 win over the Dolphins early due to a wrist injury.

Smoot (toe) was a full participant in Saturday's practice does not carry an injury designation into Monday's game against the Jaguars.

Smoot (toe) was limited during practice Thursday.

Smoot (toe) has been ruled out for Thursday's game against the Dolphins, Jay Skurski of The Buffalo News reports.

Head coach Sean McDermott told reporters Monday that Smoot (toe) is trending towards not playing in Thursday night's matchup with the Dolphins, Maddy Glab of the Bills' official site reports.

Smoot (toe) has been ruled out for Sunday's regular-season opener against the Cardinals.

Smoot (toe) didn't practice Friday and is listed as questionable ahead of Sunday's game against the Cardinals.

Smoot signed a one-year deal with the Bills on Friday, Alec White & Maddy Glab of the team's official site reports.