Mahomes (ankle) was a full participant in Tuesday's practice.
Mahomes (ankle) is inactive for Sunday's game against the Broncos.
Mahomes (ankle) is listed as doubtful for Sunday's contest at Denver.
Coach Andy Reid said Friday that Mahomes (ankle) won't play Sunday at Denver, Charles Goldman of AtoZSports.com reports.
Mahomes (ankle) was limited at practice Wednesday.
Mahomes won't start Sunday's regular-season finale against the Broncos, Matt McMullen of the Chiefs' official site reports.
The Chiefs are likely to rest Mahomes and other key starters dealing with minor injuries during their Week 18 game in Denver, Jay Glazer reported on "Fox NFL Sunday."
Mahomes completed 29 of 38 pass attempts for 320 yards and three touchdowns while rushing for 12 yards with his only carry in Wednesday's 29-10 win over the Steelers.
Mahomes completed 28 of 41 passes for 260 yards and one touchdown in Saturday's 27-19 win over the Texans. He also rushed five times for 33 yards and a touchdown.
Mahomes (ankle) doesn't carry an injury designation for Saturday's game against the Texans, Adam Teicher of ESPN.com reports.