Cleveland placed Hughlett (ribs) on its injured reserve list Wednesday.
Hughlett (ribs) has been ruled out for the remainder of Sunday's game against the Commanders, Daniel Oyefusi of ESPN.com reports.
Hughlett agreed Friday with the Browns on a four-year contract extension, Mary Kay Cabot of The Cleveland Plain Dealer reports.
Hughlett was moved back to the active roster Tuesday.
Hughlett has been placed on the reserve/COVID-19 list on Monday.
Hughlett was activated off the reserve/COVID-19 list Thursday, Scott Petrak of the Elyria Chronicle-Telegram reports.
The Browns placed Hughlett (undisclosed) on the reserve/COVID-19 list Wednesday, Nate Ulrich of the Akron Beacon Journal reports.
Hughlett signed a six-year contract with the Browns on Thursday, Adam Caplan of ESPN reports.