Cook rushed 19 times for 80 yards and a touchdown and brought in one of three targets for five yards in the Bills' 30-20 win over the Colts on Sunday.
Cook rushed 10 times for 44 yards and caught five of six targets for 25 yards in Sunday's 30-27 win over the Dolphins.
Cook (toe) doesn't have an injury designation for Sunday's contest against the Titans, while rookie fourth-rounder Ray Davis (calf) is listed as questionable, Alec White of the Bills' official site reports.
Cook (toe) practiced fully Thursday.
Cook (toe) was listed as limited in Wednesday's walk-through.
Cook (toe) will participate in Wednesday's walk-through, but coach Sean McDermott said the real test will come Thursday when the Bills hold their first real practice of the week, Jay Skurski of The Buffalo News reports.
Bills head coach Sean McDermott said Tuesday that he's hopeful Cook (toe) will be available to play Sunday against the Titans, Matt Parrino of The Syracuse Post-Standard reports.
Cook (toe) is inactive for Monday night's game against the Jets.
Cook was a limited participant in practice Saturday and is questionable for Monday night's game against the Jets, Katherine Fitzgerald of The Buffalo News reports.
Cook is expected to practice in limited fashion Saturday and is trending toward playing Monday against the Jets, Adam Schefter of ESPN reports.