Pierce went without a reception on four targets in Saturday's 23-19 loss to the Texans.
Pierce caught one pass for a 58-yard touchdown on one target in Sunday's 23-20 win over the Raiders.
Pierce brought in three of seven targets for 30 yards in the Colts' 29-10 loss to the Falcons on Sunday.
Pierce could serve as the Colts' No. 1 receiver Sunday against the Falcons with Michael Pittman (concussion/shoulder) set to miss his first game of the season, James Boyd of The Athletic reports.
Pierce had one reception for 13 yards on five targets in Saturday's win over Pittsburgh.
Pierce had four receptions for 27 yards on six targets in Sunday's win against Tampa Bay.
Pierce caught his only target for 21 yards in Sunday's 10-6 win over the Patriots.
Pierce (ankle) is active for Sunday's game against the Patriots in Frankfurt, Germany, Kevin Bowen of 107.5 The Fan Indianapolis reports.
Pierce (ankle) is listed as questionable for Sunday's game against the Patriots in Frankfurt, Germany.
Pierce was a limited participant at practice Thursday due to an ankle injury.